577: Something Only I Can See

Ira Glass

When Jeffrey was 22 he had this rare problem with his eyes, and doctors had to use lasers to fix vessels that were bleeding at the back of his left eye which worked great. But not long after, on a cold, bright winter day, he came into his house from the cold and saw this color.

Ira Glass

Got that? Green, but not green.

Ira Glass

He said that if you've ever had a migraine headache, it can come with a kind of colorful, sparkly static. It was like that. Fireworks. But really, he said, he's never done a good job describing this. How do you describe a color that only you have seen?

Ira Glass

When you see something that nobody else can see, it can be terrifying. And Jeffrey was scared that maybe something was seriously deteriorating with his vision. But once it became clear that he was going to be fine and he was going to be able to see, he had this other impulse-- to show his friends. To share it.

Ira Glass

Of course, when you see something that other people can't, you're stuck. I think for most people, you want to tell somebody. You want to share it. You want to do something.

Today no our program, we have three stories of people in this exact situation-- one involving science, one involving comedy, one involving angels. These people see something nobody else can and they cannot stop themselves. They can't shut up about it.

From WBEZ Chicago, it's This American Life. I'm Ira Glass. Stay with us.

Ira Glass

Act One, Do These Genes Make Me Look Fatless?

Well, let's kick things off with this story of somebody who not only sees something that nobody else sees, when she tells other people about the stuff she see, they don't buy it. Investigative reporter David Epstein explains.

David Epstein

I wrote a book called The Sports Gene. It's partly about how some super-athletes are genetically different from the rest of us. They have super genes. They're physiological freaks.

I was deluged with emails from parents wanting to know how they could find out if their child had Michael Jordan genes. A coach wrote offering up his players as guinea pigs for genetic experimentation. There were so many unhinged email coming in that I pretty much stopped opening them.

And then I got this one that had the subject heading, "Olympic Medalist and Muscular Dystrophy Patient with the Same Mutation" I opened it, figuring it would be a link to some article that I'd missed in my reporting. Instead, it was a note from a 39-year-old Iowa mother. Her name was Jill Viles. She was the muscular dystrophy patient, and she had a wild theory linking her genes to an Olympic sprinter named Priscilla Lopes-Schliep, and she wanted to send more info.

Sure, I said. Send it along. Why not?

Days later, a package arrived-- a 19-page illustrated bound packet. I thumbed through it. It was a little weird-- hand-drawn diagrams with cutouts of little cartoon weightlifters representing protein molecules, old photos of herself and her siblings, the original pictures, not copies. There was a detailed medical history, and it was clear she knew some serious science. She described in detail how proteins function. She referred to gene mutations by their specific DNA addresses, the way a scientist would.

And then I landed on page 14. There were two photos-- one of Jill in a royal blue bikini, sitting on a beach. Her torso looks normal, but her arms, it's like they're on the wrong body, like the stick arms on a snowman. Her legs, too, are so thin that her knee joint is wider than her thigh. Those legs can't possibly hold her upright, I thought.

The other picture was of Priscilla Lopes-Schlip, who'd been ranked the best hurdler in the world. In 2008, she won the bronze medal in the 100-meter hurdles at the Olympics in Beijing. In the photo, she's in mid-stride. It's hard to describe just how muscular she looks. Picture all the muscle you can imagine on a woman. Now picture more.

In that photo, Priscilla's like the vision of a superhero that a third-grader might draw-- huge muscles bursting from her thighs, like her skin can barely contain all of the power beneath it; ropey veins snaking along her biceps. This is the woman Jill believed she shared the same genetic code with. Jill, remember, whose arms and legs are like sticks.

David Epstein

All Jill's life, doctors had been mystified by her case. They had no idea how her muscle disease worked, much less how to treat it. She didn't know her disease came from a rare genetic mutation. And she wanted to reach Priscilla, because, looking at photos of Priscilla, seeing her body, she saw clues that made her believe Priscilla had the same mutation. If Priscilla did, if Jill was right, then scientists might figure out what was making Jill's muscles shrink and Priscilla's muscles balloon. And maybe people like Jill could someday be helped.

The whole thing seemed like a long shot, so I reached out to Robert Green, a geneticist at Harvard who I got to know while writing my book. He's an important proponent of people being allowed to get their own genetic tests. But after looking at the pictures of Jill and Priscilla, he thought Jill was almost certainly wrong. He doubted they had anything in common. And science aside, he had other concerns.

David Epstein

Of course, this is a very polite way of saying, maybe she's a nut job. I wondered the same thing. How could you not? The idea that an Iowa housewife working off Google Images would make a medical discovery about a professional athlete, whose body has been obsessively examined for years by a small army of doctors and athletic trainers, it seemed pretty ludicrous. But the fact is people with MDs and PhDs have been telling Jill that her theories are ludicrous pretty much her whole life.

Jill was born in 1974. At first, everything was great. She met all the normal baby milestones. She sat, crawled, and walked on time. Then at age four, she started stumbling and tripping all the time, constantly falling flat on her face.

David Epstein

This is Jill.

David Epstein

Jill's dad remembered that he'd had some problems walking around the same age, which his doctors had said was the result of a very mild case of polio. But Jill's troubles were much worse than her dad's had ever been. And no one could give them an answer.

Her pediatrician was stumped. He suggested they take her to the Mayo Clinic. They were stumped there, too. They tested the whole family, and found that Jill and her brother and her dad all had signs of muscle damage. But Jill was the only one having trouble walking. It might be muscular dystrophy, the doctors thought, but that didn't usually show up this way in little girls.

David Epstein

Jill went back to the Mayo Clinic every year, and it was always the same. There was nothing the doctors could do, nothing new they could tell her. The constant falling eventually stopped, but it was replaced by a burning sensation in her legs. And while she was growing in height like a normal girl, the fat on her arms and legs was vanishing.

By the time she was eight, her arms and legs were so skinny that other kids could wrap their fingers around her wrists and ankles. By age 12, veins were popping out of her legs. Kids asked how it felt to be old. And then her muscles started to fail again.

David Epstein

Jill didn't even bother to tell her parents what was happening. She knew there was nothing there the doctors could do about it. By the end of that summer, the symptoms eased up. She could walk OK again. She started looking for answers on her own, but she did it the way a kid would.

David Epstein

By the time she went to college, Jill had maxed out at 5'3" and about 87 pounds. She decided that if she was going to figure out what was happening with her body, she'd have to do it herself. So during Jill's first semester, she set up camp in the library. She began poring over every textbook and scientific journal article she could find on different kinds of muscle disease.

David Epstein

She did this for months, going article by article, like a police officer driving up and down every street doing a grid search. But nothing really fit, until she came to a page in a medical journal about an extremely rare type of muscular dystrophy called Emery-Dreifuss.

David Epstein

The journal described the three hallmarks of Emery-Dreifuss patients. They couldn't touch their chins to their chests, or their heels to the floor, and their arms were perpetually bent at the elbow.

David Epstein

That is, elbows that don't bend and feet slanted to fit into high heels.

David Epstein

Emery-Dreifuss patients, Jill learned, often dropped dead of heart failure. She became obsessed with reading about it. Before she went home for college break, she stuffed her bag full of medical books and journal articles.

David Epstein

He had always thought the stiffness in his muscles and heart troubles were unrelated.

David Epstein

They went to the Iowa Heart Center, where doctors put a heart monitor on Jill's father. His pulse rate dropped below 30 beats per minute, which meant he was either about to win the Tour de France, or he was about to drop dead. He had a pacemaker put in immediately.

David Epstein

This is Jill's mom, Mary.

David Epstein

The Iowa Heart Center wasn't set up to confirm whether or not her family had Emery-Dreifuss. That wasn't their specialty. So she went looking for someone who could. Remember, she was 19.

David Epstein

It might seem rude that a doctor would refuse even to look, but at the time, most doctors believed Emery-Dreifuss only occurred in men. Also, this was a self-diagnosis coming from a teenager-- a defiant teenager.

David Epstein

In a reading binge, Jill had come across a group of researchers working out of Italy. They were looking for families with Emery-Dreifuss to study, hoping to locate the gene that causes the disease. Jill decided to write to them. She mapped out a family tree, noting the symptoms she saw in her father, two younger brothers, and a younger sister. Then she stripped down to her underwear.

David Epstein

Up to this point, the Italians had only collected four other families to study, so they were thrilled to hear from Jill and they immediately wrote back. From the letter, it seems like they think she's a scientist who has access to a lab. They asked, can you send us DNA? If you cannot prepare DNA, just send fresh blood.

But 19-year-old Jill soon learned you can't just go to the local hospital and say draw my blood. I want to send it to Europe. So Jill convinced a nurse friend to smuggle needles and test tubes to her house. They filled them up with samples of her family's blood and shipped them off to Italy.

Today, you can sequence an entire genome in a few days. But back in the mid-1990s, not so much. It was four years before Jill heard something definitive back from the Italians. They confirmed she had Emery-Dreifuss. She'd been right all these years, despite everyone telling her otherwise.

David Epstein

The researchers had discovered the genetic cause of Jill's illness, a gene called the lamin gene. What makes the lamin gene really important is that it affects the command center inside every cell in your body. This turns other genes on and off like light switches, changing the way they build fat and muscle.

Jill's lamin gene has a typo in it, a serious one. Along the spiraling ladders of her DNA-- the 3 billion Gs, Ts, As, and Cs that make up Jill's genome-- she had one letter in the wrong place.

David Epstein

Soon after, Jill got an internship in a lab at Johns Hopkins that was mapping diseases associated with the lamin gene . The lab director had heard about Jill's research on herself and saw a chance to have not only a dogged intern in the lab, but also their very own real-life lamin mutant.

Jill's job was to sift through scientific journals and find any references that had been linked to a lamin mutation. Sitting there day after day reading, she came across an incredibly rare disease, a disorder called partial lipodystrophy. It causes the arms and legs to look as if all the fat on them has been melted away, leaving veins and muscle to stand out.

Looking at photos of patients with the disease, all Jill could think was that these people looked like her family members. Could Jill and her family have not just one, but two rare genetic diseases? The odds of getting one of them was one in a million. The odds of getting the other is one in at least a million. And the odds of getting both together? There haven't been enough human beings in the history of our species that anyone should ever get both.

So just like before, when Jill discovered Emery-Dreifuss, she zeroed in on a photo in a medical article and saw herself in it. And just like before, she tried to get confirmation from doctors. She tried to tell scientists that she had the second rare disorder, partial lipodystrophy. And just like before, they said no. They said that statistically there was very little chance that could be true. Instead, they diagnosed her with something a little more common.

David Epstein

So she dropped it. She stopped reading about this new disease. And before long, she stopped doing research into Emery-Dreifuss, too, mostly because the research she was doing started to freak her out. In the case studies she read, the average person with Emery-Dreifuss was dead by their early 40s. She was 25, and anxiety over this was landing her in the hospital.

David Epstein

So she went cold turkey. No more medical research, no more DIY diagnosis. She took a job as a writing instructor at local community colleges, and taught adult education classes at night. She started dating, eventually meeting the man who would become her husband. And even though there was a 50/50 chance that she would pass on the Emery-Dreifuss gene mutation, they decided to have a child.

Her pregnancy was normal, and her baby, Martin, doesn't have the disease. But after he was born, Jill really deteriorated physically. If you've ever had a muscle twitch, you know how strange it feels to not have control of your body. Jill's muscles started twitching from head to toe, sometimes for hours at a time, and she was suddenly having to hold onto her husband to steady herself.

David Epstein

By Martin's first birthday, she could barely walk.

David Epstein

At the same time, Jill's father was also losing his ability to walk. So father and daughter transitioned to life in motorized scooters. Jill says her dad was discouraged for the first time in his life. After a visit with a neurologist, he told her, I feel like I go there just to be weighed. Then one day, she got a call from her mom, and it was about Dad.

David Epstein

On the day he passed away, Jill and her siblings and relatives gathered at her parents' house.

David Epstein

This, of course, was Priscilla. At first, Jill didn't get it, didn't see any connection with the musclebound athlete. It had been 12 years since she went cold turkey on medical research.

But a week later, Jill got curious. She started googling pictures of Priscilla-- not just running photos, but shots of her at home doing regular things, like feeding her daughter baby food.

David Epstein

It was the third time Jill saw something in a photo other people didn't see. It had happened with Emery-Dreifuss. It happened with lipodystrophy. Now she saw that she and Priscilla were both missing fat in the same places on their arms and legs. They had the exact same muscle divisions in the exact same places in the hips and butt. Jill was certain this was because they shared a mutant gene. And the only question was, why did the gene blow up Priscilla with muscles and take Jill's away?

David Epstein

I know that sounds like the plot of a Hollywood movie. In fact, it's totally the plot of Unbreakable, The Bruce Willis, Samuel L Jackson film. Jackson plays a broken-boned, physically fragile man searching for his genetic opposite, a man born so strong his body will survive any physical trauma. In the final scene, Jackson tells Willis that he's the guy.

David Epstein

So Jill wanted to enlist Priscilla in her genetic detective work, but there was a practical problem. She had no idea how to go about reaching her.

David Epstein

A full year passed. And then Jill happened to be in earshot of her television when I started yammering about athletes and genetics on Good Morning America.

David Epstein

Jill reached out to me with her request, and I did happen to have a way to get it to Priscilla-- through her agent.

David Epstein

This, of course, is Priscilla.

David Epstein

Jill sent Priscilla the same bound packet that she sent me. And it wasn't any of the cryptic science that got to Priscilla. It was the childhood stories Jill shared about kids pointing at the veins in her legs. Priscilla said she always used to come home sad and crying. She'd ask her parents--

David Epstein

Once she grew up, the finger-pointing didn't end. It just morphed. When people see huge, shredded muscles like Priscilla's on an athlete, it usually means one thing-- steroids. And Priscilla's been dogged by doping rumors since college. After she won the Olympic bronze medal in Beijing, some media outlets in Europe began to openly accuse her. And of course, there were the not-so-furtive glances.

David Epstein

At the world championships in Berlin in 2009, Priscilla was drug-tested just minutes before winning a silver medal. There's not even supposed to be any drug testing that close to the race. Then the following month, at a meet-and-greet, someone stole her training journal out of her bag. It was at the very bottom, underneath expensive workout clothes and shoes, none of which were taken. Why steal a training journal? As someone who's covered a lot of doping stories, I'm convinced someone thought the journal contained her steroid regimen.

Priscilla and Jill spent a lot of time talking on the phone. And eight months after I first put them in touch, they finally met in person in Toronto, where Priscilla lived. They picked a hotel lobby. Jill arrived first.

David Epstein

Priscilla felt the same way.

David Epstein

It took a year to find a doctor to test Priscilla. Finally, Jill went to a medical conference and approached the foremost expert in lipodystrophy, Dr. Abhimanyu Garg, who runs a lab at University of Texas Southwestern Medical Center. He agreed to do the testing.

The results showed that Jill had been right. She and Priscilla do have a genetic connection. They each have a single typo on the same one of our 23,000 genes, the lamin gene. It's not the exact same typo, but they're almost right next to each other. That splinter of distance and typo location makes the difference between Jill's muscles and Priscilla's muscles. It's why Jill has Emery-Dreifuss and Priscilla doesn't.

But Dr. Garg also found that they do share a disease. They both have the exact same rare subtype of lipodystrophy, the disease that wastes away fat. Jill had been told it had nothing to do with her back when she was a summer intern at Johns Hopkins. Jill had been right about that all along. Dr. Garg called Priscilla immediately to give her the news. He caught her at the mall shopping with her kids.

David Epstein

Then he told Priscilla that, despite her rigorous training regimen, her untreated lipodystrophy left her with 15 times the normal amount of fat in her blood. Her next hamburger could land her in the emergency room. She was that close.

In other words, once again, Jill steered someone away from a medical disaster. She'd saved her dad's life. Now, using the cutting-edge medical tool known as Google Images, she caused the most intense medical intervention in the life of this professional athlete.

David Epstein

Scientists can learn all sorts of things by studying very rare genetic diseases. For instance, research on a rare gene mutation that gives people freakishly low cholesterol levels led to a drug that treats high cholesterol. An Alzheimer's treatment might come from studying a small group of people in Iceland. They have a super-rare mutation that protects their brains.

Recently, a group of scientists started something called the Matchmaker Exchange. It's a kind of OkCupid for rare diseases, where people can share genetic and symptom information with each other and doctors. The hope is that it will spark new discoveries.

David Epstein

That's Etienne Lefai, a molecular biologist in France. He does super-technical work on a protein with the lovely name SREBP-1. It affects fat storage. And his research team showed that messing around with it can create mice with almost no muscle at all, or potentially little rodent Schwarzeneggers. When Jill first reached him, she told him that he may have found the actual biological mechanism that makes her and Priscilla so different.

David Epstein

Of course, this is so different than the skepticism Jill's gotten from scientists and doctors for decades. I checked back in with one of the doubters, Robert Green-- you know, the geneticist at Harvard I first talked to who was so incredulous about any genetic connection between Jill and Priscilla. I email him the results of Priscilla's genetic test.

David Epstein

About a week after I talked to Doctors Green and Lefai, I played those conversations back for Jill

David Epstein

Jill says she's proved her point. She says she's retiring from DIY medical research. She gave me the same line that professional athletes use. "I want to spend more time with my family." But her mother doesn't believe she's retiring, nor does Dr. Lefai. And I certainly don't believe her.

Recently, Jill sent me an email. She picked up on a tidbit in a very technical scientific paper about potentially reversing muscular dystrophy. "I don't want to read too much into this," she wrote me, "but, of course, I'm curious."

Ira Glass

David Epstein. The book that he wrote that kicked all this off is The Sports Gene-- Inside the Science of Extraordinary Athletic Performance. He has more about Jill and Priscilla, including jaw-dropping photos, at propublica.org.

In the years since we first ran this story, as predicted, Jill has gone back to the research game. She still talks to Priscilla, who recently retired from track and field.

Coming up. OK, you know how we started today's program with the color green that was not green? After the break, Tig Notaro finds a joke that is also not a joke. That's from WBEZ Chicago when our program continues.

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Ira Glass

It's This American Life. I'm Ira Glass. Each week on our program, of course, we choose a theme, bring you different kinds of stories on that theme. Today's show, "Something Only I Can See." We have stories of people who spot something that no one else has noticed and then feel compelled to tell somebody, show somebody, do something about it.

We've arrived at Act Two of our program. Act Two, Mom Jokes.

So comedians don't usually laugh at their own jokes as a rule. It's gauche. It makes things less funny as a rule. But, as Van Halen once said, "rules are for fools." Tig Notaro has been on our program before. She talked to Nancy Updike about a recent rule-breaking addition to one of her stand-up shows.

Nancy Updike

As we know, 58% of all important events in America start in the car. Tig and her fiancee Stephanie were driving along with--

Nancy Updike

This went on for a couple of minutes-- laughing, catching her breath, almost starting to tell the joke, and then more uncontrollable laughing, until everyone in the car was laughing just watching her trying to tell the joke.

Nancy Updike

And then Tig had a vision of what needed to happen at her next stand-up show.

Nancy Updike

Two weeks after the car ride, Tig made her vision come true. Carol walks onto the stage of a comedy club in Los Angeles called Largo. She's not in jeans. She's not in comedy club casual. She is a tasteful mom in cropped white pants carrying her purse. She is a civilian.

Nancy Updike

Carol knew two things about her own joke when she walked onto the stage. She knew that it was not a very good joke. She told Tig when Tig was trying to convince her to come on stage. She said, this is nuts. Nobody's going to laugh. Carol also knew that she herself could not tell the joke without laughing. She was living the mystery many of us have lived-- the all-the-way-inside joke. The joke that is funny beyond reason in your head and you cannot communicate the funniness, because you don't even understand it. That's what Carol knew. So she was nervous.

Nancy Updike

Of course, everything Carol is doing is usually comedy death-- explaining the joke, exposing the machinery of it-- and she is killing.

Nancy Updike

Carol's rocking backward and slapping her knee, she's laughing so hard. She has spent the last 10 minutes giving caveats, laying out everything the joke has going against it, why it's no good. And then when the joke comes into her head, as she's about to tell it, none of that matters.

Nancy Updike

All jokes start as inside jokes, inside someone's head. Some of them make it out into the world and catch on, and that's comedy, the way it usually works. This was a rare chance to root for the other kind of joke-- the nonstarter, the crush no one understands, including you. Your rational brain can make its rational arguments, and then what? You stop having feelings you don't understand? No.

Ira Glass

Nancy Updike is one of the producers of our program. Tig Notaro's book, I'm Just a Person, came out last summer.

Ira Glass

Act Three, Earth Angel.

So we close today's program with this story about somebody who sees and believes something that nobody else does. From Etgar Keret, it's read for us by actor Alex Karpovsky.

Alex Karpovsky

On Bernadette Avenue, right next to the central bus station, there's a hole in the wall. There used to be an ATM there once, but it broke or something, or else nobody ever used it. So the people from the bank came in a pickup and took it and never brought it back. Somebody once told Udi that if you scream a wish into this hole, it comes true. But Udi didn't really buy that.

The truth is that once, on his way home from the movies, he screamed into the hole in the wall that he wanted Daphne Remalt to fall in love with him, and nothing happened. And once, when he was feeling really lonely, he screamed into the hole in the wall that he wanted to have an angel for a friend. And an angel really did show up right after that, but he was never much of a friend. And he'd always disappear just when Udi really needed him.

This angel was skinny and all stooped, and he wore a trench coat the whole time to hide his wings. People in the street were sure he was a hunchback. Sometimes when they were just the two of them, he'd take the coat off. Once, he even let Udi touch the feathers on his wings, but when there was anyone else in the room, he always kept it on. Kids asked him once what he had under his coat, and he said it was a backpack full of books that didn't belong to him and that he didn't want them to get wet.

Actually, he lied all the time. He told Udi such stories you could throw up-- about places in heaven; about people who, when they go to bed at night, leave the keys in the ignition; about cats who aren't afraid of anything and don't even know the meaning of scat. The stories he made up were something else. And to top it all, he'd cross-his-heart-and-hope-to-die.

Udi was nuts about him and always tried hard to believe him, even lent him some money a couple of times when he was hard up. As for the angel, he didn't do a thing to help Udi. He just talked and talked and talked, rambling off his harebrained stories. In the six years he knew him, Udi never saw him so much as rinse a glass.

When Udi was in the army in basic training and really needed someone to talk to, the angel suddenly disappeared on him for two solid months. Then he came back with an unshaven, don't-ask-what-happened face. So Udi didn't ask, and on Saturday they sat around on the roof in their underpants just taking in the sun and feeling low. Udi looked at the other rooftops with the cable hookups and the solar heaters and the sky. It occurred to him suddenly that, in all their years together, he'd never once seen the angel fly.

"How about flying around a little?" he said to the angel. "It would make you feel better."

And the angel said, "forget it. What if someone sees me?"

"Be a sport," Udi nagged. "Just a little. For my sake." But the angel just made this disgusting noise from the inside of his mouth and shot a gob of spit and white phlegm at the tar-covered roof.

"Never mind," Udi sulked. "I bet you don't know how to fly, anyway."

"Sure I do," the angel shot back. "I just don't want people to see me, that's all."

On the roof across the way they saw some kids throwing a water bomb. "You know," Udi smiled. "Once, when I was little, before I met you, I used to come up here a lot and throw water bombs on people in the street below. I'd aim them into the space between that awning and the other one," he explained, bending over the railing and pointing down at the narrow gap between the awning over the grocery store and the one over the shoe store. "People would look up, and all they'd see was the awning. They wouldn't know where it was coming from."

The angel got up too and looked down into the street. He opened his mouth to say something. Suddenly, Udi gave him a little shove from behind, and the angel lost his balance. Udi was just fooling around. He didn't really mean to hurt the angel, just to make him fly a little, for laughs. But the angel dropped the whole five floors, like a sack of potatoes. Stunned, Udi watched him lying there on the sidewalk below. His whole body was completely still, except the wings, that were still fluttering a little. That's when he finally understood that, of all the things the angel had told him, nothing was true. That he wasn't even an angel, just a liar with wings.

Ira Glass

Alex Karpovsky reading Etgar Keret's story, "Hole in the Wall," which is collected in his book of short stories called The Bus Driver Who Wanted to be God.

Ira Glass

Our program was produced today by Stephanie Foo with Zoe Chace, Sean Cole, Neil Drumming, Chana Joffe-Walt, Miki Meek, Jonathan Menjivar, Robyn Semien, Alyssa Shipp, and Nancy Updike. Our senior producer for today's show is Brian Reed. Editing help for today's show from Joel Lovell and Julie Snyder. Our technical director is Matt Tierney. Production help from Emmanuel Dzotsi and Diane Wu. Research help from Christopher Swetala and Lu Fong. Musical help today from Damien Graef and Rob Geddis.

[ACKNOWLEDGEMENTS]

Jeff Emtman, who you heard at the beginning of our program-- the guy who saw a green that was not green-- is the host of Here Be Monsters, a podcast about fear and the unknown from KCRW. Our website, thisamericanlife.org. This American Life is delivered to public radio stations by PRX, the Public Radio Exchange.

Support for This American Life comes from Lagunitas Brewing Company, committed to keeping the pub in public radio by offering curious ales and lagers for those who appreciate hearing and telling great stories. Learn more at lagunitas.com.

Thanks, as always, to our program's co-founder Mr. Torey Malatia. You know, he and I were on a flight together this week and we got delayed on the tarmac for three hours. It got to the point where Torey started calling out to the cockpit and heckling the pilot.

Alex Karpovsky

How about flying around a little? It would make you feel better.

Ira Glass

I'm Ira Glass. Back next week with more stories of This American Life.